Our SAB Members
Our SAB consists of scientific experts that provide valuable expertise and help us shape the future of next generation sequencing.
Adam Hall, PhD
Associate Professor, Biomedical Engineering
Wake Forest School of Medicine
Dr. Hall’s lab develops translational applications for nano- and microtechnologies, focusing on two key platforms: (1) solid-state nanopores, which the lab employs for a broad range of analyses at the single-molecule level including characterization of important biological sugars like hyaluronan and detection of nucleic acid biomarkers for cancer and infectious disease, and (2) 3D cell culture constructs integrated with microfluidic systems, which the lab uses to study cancer progression and develop ex vivo approaches to personalized medicine.
Steven Boxer, PhD
Camille Dreyfus Professor of Chemistry
Department of Chemistry
His research interests are in biophysics: the interface of physical chemistry, biology and engineering. Topics of current interest include: electrostatics and dynamics in proteins; excited state dynamics of green fluorescent protein, especially split GFP, with applications in biotechnology; electron and energy transfer mechanisms in photosynthesis; and the fabrication of artificial systems to simulate, manipulate, and image biological membranes. He has served on the scientific advisory board of many start-ups in the general area of biotechnology, and as an advisor to the Howard Hughes Medical Institute, the National Institutes of Health and the National Science Foundation. He is an elected Fellow of the American Academy of Arts and Sciences, the Biophysical Society and the National Academy of Sciences.
Michael Snyder, PhD
Stanford Ascherman Professor and Chair of Genetics
Director of the Center of Genomics and Personalized Medicine
Dr. Snyder is a leader in the field of functional genomics and multiomics, and one of the major participants of the ENCODE project. His laboratory was the first to perform a large-scale functional genomics project in any organism and has developed many technologies in genomics and proteomics. These include the development of proteome chips, high resolution tiling arrays for the entire human genome, methods for global mapping of transcription factor (TF) binding sites (ChIP-chip now replaced by ChIP-seq), paired end sequencing for mapping of structural variation in eukaryotes, de novo genome sequencing of genomes using high throughput technologies and RNA-Seq. These technologies have been used for characterizing genomes, proteomes and regulatory networks. Seminal findings from the Snyder laboratory include the discovery that much more of the human genome is transcribed and contains regulatory information than was previously appreciated (e.g. lncRNAs and TF binding sites), and a high diversity of transcription factor binding occurs both between and within species.
William Greenleaf, PhD
Associate Professor in the Genetics Department, with a courtesy appointment in the Applied Physics Department
Stanford University School of Medicine
The Greenleaf laboratory at Stanford focuses on developing methods to probe both the structure and function of molecules encoded by the genome, as well as the physical compaction and folding of the genome itself. The lab’s efforts are split between building new tools to leverage the power of high-throughput sequencing technologies and cutting-edge optical microscopies, and bringing these technologies to bear against basic biological questions by linking DNA sequence, structure, and function.